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Applying unmixing to gene expression data for tumor phylogeny inference

BACKGROUND: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall into a relatively small number of "sub-types," each characterized a roughly equivalent sequence of mutations by wh...

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Autors principals: Schwartz, Russell, Shackney, Stanley E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823708/
https://ncbi.nlm.nih.gov/pubmed/20089185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-42
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