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Does replication groups scoring reduce false positive rate in SNP interaction discovery?

BACKGROUND: Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems. Present experimental studies typically use SNP arrays wi...

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Autors principals: Toplak, Marko, Curk, Tomaz, Demsar, Janez, Zupan, Blaz
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823693/
https://ncbi.nlm.nih.gov/pubmed/20092660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-58
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