Evolution to predominance of swine influenza virus hemagglutinin mutants of predictable phenotype during single infections of the natural host.

L and H2 mutants of the A/NJ/11/76 H1N1 strain of swine influenza virus differ by having either a lysine or a glutamic acid at position 153 of the hemagglutinin glycoprotein of the virus. In two separate experiments, experimental infection of swine with various doses of the H2 mutant resulted in the...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kilbourne, E D, Easterday, B C, McGregor, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186713/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8098
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