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Antimitochondrial Autoantibodies in Pemphigus Vulgaris: A MISSING LINK IN DISEASE PATHOPHYSIOLOGY

A loss of epidermal cohesion in pemphigus vulgaris (PV) results from autoantibody action on keratinocytes (KCs) activating the signaling kinases and executioner caspases that damage KCs, causing their shrinkage, detachment from neighboring cells, and rounding up (apoptolysis). In this study, we foun...

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Detalhes bibliográficos
Main Authors: Marchenko, Steve, Chernyavsky, Alexander I., Arredondo, Juan, Gindi, Vivian, Grando, Sergei A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823510/
https://ncbi.nlm.nih.gov/pubmed/20007702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081570
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