Induced ncRNAs Allosterically Modify RNA Binding Proteins in cis to Inhibit Transcription

With the recent recognition of non-coding RNAs (ncRNAs) flanking many genes1-5, a central issue is to fully understand their potential roles in regulated gene transcription programs, possibly through different mechanisms6-12. Here, we report that an RNA-binding protein, TLS, serves as a key transcri...

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Hauptverfasser: Wang, Xiangting, Arai, Shigeki, Song, Xiaoyuan, Reichart, Donna, Du, Kun, Pascual, Gabriel, Tempst, Paul, Rosenfeld, Michael G., Glass, Christopher K., Kurokawa, Riki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823488/
https://ncbi.nlm.nih.gov/pubmed/18509338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06992
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