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TLR2 Activation Is Essential to Induce a Th1 Shift in Human Peripheral Blood Mononuclear Cells by Plant Stanols and Plant Sterols

Plant sterols may induce a Th1 shift in humans. However, whether plant stanols have similar effects as well as the underlying mechanism are unknown. We have now shown that (like sitosterol) sitostanol, both 4-desmethylsterols, induces a Th1 shift when added in vitro at physiological concentrations t...

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Autori principali: Brüll, Florence, Mensink, Ronald P., van den Hurk, Karin, Duijvestijn, Adriaan, Plat, Jogchum
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823451/
https://ncbi.nlm.nih.gov/pubmed/19948716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036343
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