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Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats

BACKGROUND AND PURPOSE: Alagebrium is a breaker of cross-links in advanced glycation endproducts. However, the acute effects of alagebrium on methylglyoxal (MG), a major precursor of advanced glycation endproducts have not been reported. MG is a highly reactive endogenous metabolite, and its levels...

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Détails bibliographiques
Auteurs principaux: Dhar, Arti, Desai, Kaushik M, Wu, Lingyun
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823362/
https://ncbi.nlm.nih.gov/pubmed/20002105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00469.x
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