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Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT(1A) receptors

BACKGROUND AND PURPOSE: Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that induces anxiolytic- and antipsychotic-like effects in animal models. Effects of CBD may be mediated by the activation of 5-HT(1A) receptors. As 5-HT(1A) receptor activation may induce antidepressant...

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Bibliographic Details
Main Authors: Zanelati, TV, Biojone, C, Moreira, FA, Guimarães, FS, Joca, SRL
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823358/
https://ncbi.nlm.nih.gov/pubmed/20002102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00521.x
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