A comparison of the effects of ibuprofen and rofecoxib on rabbit fibula osteotomy healing

Background and purpose Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase (COX) activity, which is the rate-limiting enzyme in the synthesis of prostaglandins. Previous studies have indicated that NSAID therapy, and in particular NSAIDs that specifically target the inflammatory cy...

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Bibliographic Details
Main Authors: O'Connor, J Patrick, Capo, John T, Tan, Virak, Cottrell, Jessica A, Manigrasso, Michaele B, Bontempo, Nicholas, Parsons, J Russell
Format: Artigo
Language:Inglês
Published: Informa Healthcare 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823333/
https://ncbi.nlm.nih.gov/pubmed/19916696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17453670903316769
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