Drug-Induced Plasticity Contributing to Heightened Relapse Susceptibility: Neurochemical Changes and Augmented Reinstatement in High-Intake Rats

A key in understanding the neurobiology of addiction and developing effective pharmacotherapies is revealing drug-induced plasticity that results in heightened relapse susceptibility. Previous studies have demonstrated that increased extracellular glutamate, but not dopamine, in the nucleus accumben...

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Autors principals: Madayag, Aric, Kau, Kristen S., Lobner, Doug, Mantsch, John R., Wisniewski, Samantha, Baker, David A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823262/
https://ncbi.nlm.nih.gov/pubmed/20053903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1342-09.2010
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