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Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
Craniorachischisis is a rare but severe birth defect that results in a completely open neural tube. Mouse mutants in planar cell polarity (PCP) signaling components have deficits in the morphological movements of convergent extension (CE) that result in craniorachischisis. Using a forward-genetic sc...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823131/ https://ncbi.nlm.nih.gov/pubmed/19966784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2002 |
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