Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

Craniorachischisis is a rare but severe birth defect that results in a completely open neural tube. Mouse mutants in planar cell polarity (PCP) signaling components have deficits in the morphological movements of convergent extension (CE) that result in craniorachischisis. Using a forward-genetic sc...

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Bibliographic Details
Main Authors: Merte, Janna, Jensen, Devon, Wright, Kevin, Sarsfield, Sarah, Wang, Yanshu, Schekman, Randy, Ginty, David D.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823131/
https://ncbi.nlm.nih.gov/pubmed/19966784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2002
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