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Holliday junctions in FLP recombination: resolution by step-arrest mutants of FLP protein.

The FLP "recombinase" of the 2-micron circle yeast plasmid can resolve synthetic FLP site-Holliday junctions. Mutants of the FLP protein that are blocked in recombination but are normal in substrate cleavage can also mediate resolution. The products of resolution by these mutants are almost exclusiv...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jayaram, M, Crain, K L, Parsons, R L, Harshey, R M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282308/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3054874/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.7902
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