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Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications.

Proteases that are encoded by animal picornaviruses and plant como- and potyviruses form a related group of cysteine-active-center enzymes that are essential for virus maturation. We show that these proteins are homologous to the family of trypsin-like serine proteases. In our model, the active-site...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bazan, J F, Fletterick, R J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186696/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.7872
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