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Serum Amyloid A Regulates Granulomatous Inflammation in Sarcoidosis through Toll-like Receptor-2

Rationale: The critical innate immune mechanisms that regulate granulomatous inflammation in sarcoidosis are unknown. Because the granuloma-inducing component of sarcoidosis tissues has physicochemical properties similar to those of amyloid fibrils, we hypothesized that host proteins capable of form...

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Hlavní autoři: Chen, Edward S., Song, Zhimin, Willett, Matthew H., Heine, Shannon, Yung, Rex C., Liu, Mark C., Groshong, Steve D., Zhang, Ying, Tuder, Rubin M., Moller, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822973/
https://ncbi.nlm.nih.gov/pubmed/19910611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200905-0696OC
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