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E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung

BACKGROUND: Interactions of endothelial selectins with tumour cell glycoconjugates have been shown to have a major role in tumour cell dissemination in previous experiments. However, experiments validating this observation were limited in value, as ‘metastases’ in these experiments were artificially...

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Autori principali: Köhler, S, Ullrich, S, Richter, U, Schumacher, U
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822933/
https://ncbi.nlm.nih.gov/pubmed/20010946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605492
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