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Intracellular pH in human skeletal muscle by 1H NMR.

We report here the in vivo observation of the imidazole protons (C-2 and C-4) of carnosine (beta-Ala-His) by 1H NMR at 4.7 T in human skeletal muscle. The relationship between the pH and chemical shift of the C-2 and C-4 resonances was determined analytically. These titration curves were used to mea...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pan, J W, Hamm, J R, Rothman, D L, Shulman, R G
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282291/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.7836
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