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Covalent binding of the endogenous estrogen 16 alpha-hydroxyestrone to estradiol receptor in human breast cancer cells: characterization and intranuclear localization.

The interactions of 16 alpha-hydroxyestrone (16 alpha-OHE1), a metabolite of estradiol (E2), with estrogen receptors (ERs) were compared in this study to the classic E2-receptor mechanism in human breast cancer cells MCF-7 in culture. When MCF-7 cells were incubated with radioinert 16 alpha-OHE1 or...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Swaneck, G E, Fishman, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 1988
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282290/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.7831
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