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Impaired Expression of Neuroprotective Molecules in the HIF-1α Pathway following Traumatic Brain Injury in Aged Mice

Elderly traumatic brain injury (TBI) patients have higher rates of mortality and worse functional outcome than non-elderly TBI patients. The mechanisms involved in poor outcomes in the elderly are not well understood. Hypoxia-inducible factor–1 alpha (HIF-1α) is a basic helix-loop-helix transcriptio...

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Detalhes bibliográficos
Main Authors: Anderson, Joshua, Sandhir, Rajat, Hamilton, Eric S., Berman, Nancy E.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822808/
https://ncbi.nlm.nih.gov/pubmed/19203226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0765
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