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Hemagglutinin polymorphism as the basis for low- and high-yield phenotypes of swine influenza virus.

Single amino acid substitutions at the rim of the receptor binding site of the hemagglutinin molecule of swine influenza virus markedly influence the replicative capacity of the virus in chicken embryos, Madin-Darby canine kidney cells (MDCK), and swine as well as its antigenic phenotype. Mutants of...

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Detalhes bibliográficos
Main Authors: Kilbourne, E D, Taylor, A H, Whitaker, C W, Sahai, R, Caton, A J
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC282277/
https://ncbi.nlm.nih.gov/pubmed/3174662
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