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Damaged-DNA Binding Protein-2 Drives Apoptosis Following DNA Damage

Apoptosis induced by DNA damage is an important mechanism of tumor suppression and it is significant also in cancer chemotherapy. Mammalian cells activate the pathways of p53 to induce apoptosis of cells harboring irreparable DNA damages. While p53 induces expression of various pro-apoptotic genes a...

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Autori principali: Bagchi, Srilata, Raychaudhuri, Pradip
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822757/
https://ncbi.nlm.nih.gov/pubmed/20205757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-3
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