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Correlation of Structural Stability with Functional Remodeling of High-Density Lipoproteins: The Importance of Being Disordered

High-density lipoproteins (HDLs) are protein-lipid assemblies that remove excess cell cholesterol and prevent atherosclerosis. HDL are stabilized by kinetic barriers that decelerate protein dissociation and lipoprotein fusion. We propose that similar barriers modulate metabolic remodeling of plasma...

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Detalhes bibliográficos
Main Authors: Guha, Madhumita, Gao, Xuan, Jayaraman, Shobini, Gursky, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822716/
https://ncbi.nlm.nih.gov/pubmed/18839964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8014746
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