Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole

Previously, we showed that sulfaphenazole (SUL), an antimicrobial agent that is a potent inhibitor of cytochrome P4502C9, is protective against ischemia-reperfusion (I/R) injury (Ref. 15). The mechanism, however, underlying this cardioprotection, is largely unknown. With evidence that activation of...

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Autori principali: Huang, Chengqun, Liu, Wayne, Perry, Cynthia N., Yitzhaki, Smadar, Lee, Youngil, Yuan, Hua, Tsukada, Yayoi Tetsuo, Hamacher-Brady, Anne, Mentzer, Robert M., Gottlieb, Roberta A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822573/
https://ncbi.nlm.nih.gov/pubmed/20008275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00716.2009
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