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Characterization of the PcCdc42 small G protein from Pneumocystis carinii, which interacts with the PcSte20 life cycle regulatory kinase

Pneumocystis carinii (Pc) causes severe pneumonia in immunocompromised hosts. The binding of Pc trophic forms to alveolar epithelial cells is a central feature of infection, inducing the expression and activation of PcSte20, a gene participating in mating, proliferation, and pseudohyphal growth. In...

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Detalhes bibliográficos
Main Authors: Krajicek, Bryan J., Kottom, Theodore J., Villegas, Leah, Limper, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822561/
https://ncbi.nlm.nih.gov/pubmed/19915161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00191.2009
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