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Reductions in laminin β2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose
Insulin-like growth factor binding protein-5 (IGFBP-5) mediates mesangial cell migration through activation of cdc42, and laminin421 binding to α(6)β(1)-integrin (Berfield AK, Hansen KM, Abrass CK. Am J Physiol Cell Physiol 291: C589–C599, 2006). Because glomerular expression of laminin β(2) is redu...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Physiological Society
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822519/ https://ncbi.nlm.nih.gov/pubmed/19864299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00483.2009 |
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