Inactive X chromosome has the highest concentration of unmethylated Hha I sites.
A procedure enabling the highly sensitive detection of accessible restriction endonuclease sites on metaphase chromosomes is described. The procedure is based on the following: (i) a terminal deoxynucleotidyltransferase is used to add a biotinylated nucleotide (Bio-11-dUTP) tail to the 3' hydroxyl t...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3262875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7657 |
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