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Cyclic AMP-mediated endocytosis of intestinal epithelial NHE3 requires binding to synaptotagmin 1

The apical membrane Na(+)-H(+) exchanger (NHE)3 is regulated by cAMP-dependent phosphorylation, which inhibits its activity through membrane endocytosis. The clathrin complex adaptor protein synaptotagmin 1 (Syt 1) appears to be essential to this process, but little is known about its expression in...

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Auteurs principaux: Musch, Mark W., Arvans, Donna L., Wang, Yunwei, Nakagawa, Yasushi, Solomaha, Elena, Chang, Eugene B.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822502/
https://ncbi.nlm.nih.gov/pubmed/19926819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00379.2009
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