The GPA-dependent, spherostomatocytosis mutant AE1 E758K induces GPA-independent, endogenous cation transport in amphibian oocytes

The previously undescribed heterozygous missense mutation E758K was discovered in the human AE1/SLC4A1/band 3 gene in two unrelated patients with well-compensated hereditary spherostomatocytic anemia (HSt). Oocyte surface expression of AE1 E758K, in contrast to that of wild-type AE1, required coexpr...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Stewart, Andrew K., Vandorpe, David H., Heneghan, John F., Chebib, Fouad, Stolpe, Kathleen, Akhavein, Arash, Edelman, E. Jennifer, Maksimova, Yelena, Gallagher, Patrick G., Alper, Seth L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
Membrane Transporters, Ion Channels and Pumps
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822494/
https://ncbi.nlm.nih.gov/pubmed/19907019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00444.2009
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky