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Inhibition of Thromboxane Synthase Activity Improves Glioblastoma Response to Alkylation Chemotherapy

Thromboxane synthase (TXSA), an enzyme of the arachidonic acid metabolism, is upregulated in human glial tumors and is involved in glioma progression. Here, we analyzed the in vitro and in vivo effects of pharmacological inhibition of TXSA activity on human glioblastoma cells. Furegrelate, a specifi...

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Detaylı Bibliyografya
Asıl Yazarlar: Schmidt, Nils Ole, Ziu, Mateo, Cargioli, Theresa, Westphal, Manfred, Giese, Alf, Black, Peter M, Carroll, Rona S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press Inc. 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822453/
https://ncbi.nlm.nih.gov/pubmed/20165694
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