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What have we learned from the studies of two-state folders, and what are the unanswered questions about two-state protein folding?
Small proteins with globular structures often fold by simple all-or-none mechanisms, both in an equilibrium and a kinetic sense, despite the very large number of partly folded conformations available. This type of “two-state” folding will be discussed in terms of experimental tests, underlying molec...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822238/ https://ncbi.nlm.nih.gov/pubmed/19208936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/6/1/015001 |
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