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Modeling Species-Specific Diacylglycerol Dynamics in the RAW 264.7 Macrophage

A mathematical model of the G protein signaling pathway in RAW 264.7 macrophages downstream of P2Y(6) receptors activated by the ubiquitous signaling nucleotide uridine 5′-diphosphate is developed. The model, which is based on time-course measurements of inositol trisphosphate, cytosolic calcium, an...

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Autors principals: Callender, Hannah L., Horn, Mary Ann, DeCamp, Dianne L., Sternweis, Paul C., Brown, H. Alex
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822135/
https://ncbi.nlm.nih.gov/pubmed/19883664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.10.030
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