RalA-Exocyst Complex Regulates Integrin-Dependent Membrane Raft Exocytosis and Growth Signaling

Anchorage-dependence of cell growth is a key metastasis-suppression mechanism that is mediated by effects of integrins on growth signaling pathways [1]. The small GTPase RalA is activated in metastatic cancers through multiple mechanisms and specifically induces anchorage independence [2–4]. Loss of...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Balasubramanian, Nagaraj, Meier, Jeremy A., Scott, David W., Norambuena, Andrés, White, Michael A., Schwartz, Martin Alexander
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822103/
https://ncbi.nlm.nih.gov/pubmed/20005108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.11.016
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares