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Increased Anxiety-Like Behavior of Rats During Amphetamine Withdrawal is Reversed by CRF-2 Receptor Antagonism

Withdrawal from psychostimulants increases anxiety states, and amphetamine-treated rats show increased CRF(2) receptors in the serotonergic cell body region, the dorsal raphe nucleus (dRN). In the current study, amphetamine (2.5 mg/kg, ip, 14 days) pre-treated rats spent less time in open arms of th...

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Detalhes bibliográficos
Main Authors: Vuong, Shawn M., Oliver, Harvey A., Scholl, Jamie L., Oliver, Kathryn M., Forster, Gina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821976/
https://ncbi.nlm.nih.gov/pubmed/19958793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2009.11.036
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