Alzheimer disease tangles share immunological similarities with multiphosphorylation repeats in the two large neurofilament proteins.
Immunological and structural analyses of neurofilament (NF) proteins with greater than 500 anti-NF monoclonal antibodies (mAbs) enumerated epitopes shared by NF proteins and Alzheimer neurofibrillary tangles. We identified the multiphosphorylation domain of the rat heaviest NF subunit--tandem repeat...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1988
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2459703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7384 |
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