Heterogeneous expression of protein and mRNA in pyruvate dehydrogenase deficiency.

Deficiency of pyruvate dehydrogenase [pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating), EC 1.2.4.1], the first component of the pyruvate dehydrogenase complex, is associated with lactic acidosis and central nervous system dysfunction. Using both specific antibodies to p...

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Bibliographic Details
Published in:	Proc Natl Acad Sci U S A
Main Authors:	Wexler, I D, Kerr, D S, Ho, L, Lusk, M M, Pepin, R A, Javed, A A, Mole, J E, Jesse, B W, Thekkumkara, T J, Pons, G
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1988
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3140238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7336
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Heterogeneous expression of protein and mRNA in pyruvate dehydrogenase deficiency.

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