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The Importance of Hydrogen Bonding between the Glutamine Side-Chains to the Formation of Amyloid VQIVYK Parallel β-sheets. An ONIOM DFT/AM1 Study
[Image: see text] We report DFT calculations that indicate β-sheet formation involving the capped amino acid sequence, VQIVYK, to be due (at least in part) to cooperative H-bonding between the glutamine side chains. The sequence, VQIVYK, has been reported to be essential for the aggregation of the p...
Tallennettuna:
| Päätekijät: | , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821795/ https://ncbi.nlm.nih.gov/pubmed/20088582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909690a |
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