Isolation and characterization of human defensin cDNA clones.

Four clones that encode defensins, a group of microbicidal and cytotoxic peptides made by neutrophils, were isolated from an HL-60 human promyelocytic leukemia cDNA library. Analysis of these clones indicated that the defensins are made as precursor proteins, which must be cleaved to yield the matur...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Daher, K A, Lehrer, R I, Ganz, T, Kronenberg, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7327
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