Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: dihydrolipoamide acetyltransferase.

Primary biliary cirrhosis is a chronic, destructive autoimmune liver disease of humans. Patient sera are characterized by a high frequency (greater than 95%) of autoantibodies to a Mr 70,000 mitochondrial antigen, a component of the M2 antigen complex. We have identified a human cDNA clone encoding...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Coppel, R L, McNeilage, L J, Surh, C D, Van de Water, J, Spithill, T W, Whittingham, S, Gershwin, M E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7317
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