Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: dihydrolipoamide acetyltransferase.

Primary biliary cirrhosis is a chronic, destructive autoimmune liver disease of humans. Patient sera are characterized by a high frequency (greater than 95%) of autoantibodies to a Mr 70,000 mitochondrial antigen, a component of the M2 antigen complex. We have identified a human cDNA clone encoding...

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Main Authors: Coppel, R L, McNeilage, L J, Surh, C D, Van de Water, J, Spithill, T W, Whittingham, S, Gershwin, M E
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC282177/
https://ncbi.nlm.nih.gov/pubmed/3174635
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