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An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3

Alzheimer’s disease (AD) is the most common form of progressive dementia in the elderly. It is a neurodegenerative disorder characterized by the neuropathologic findings of intracellular neurofibrillary tangles and extracellular amyloid plaques that accumulate in vulnerable brain regions. AD etiolog...

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Détails bibliographiques
Auteurs principaux: Edwards, Todd L., Pericak-Vance, Margaret, Gilbert, Johnny, Haines, Jonathan L., Martin, Eden, Ritchie, Marylyn D.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821734/
https://ncbi.nlm.nih.gov/pubmed/19105203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30899
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