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Cholera toxin potentiates IgE-coupled inositol phospholipid hydrolysis and mediator secretion by RBL-2H3 cells.
Binding of polyvalent antigens to IgE present in Fc epsilon receptors on the surface of mast cells and the RBL-2H3 cell line triggers the exocytotic release of allergic mediators. Preincubation of RBL-2H3 cells with cholera toxin (CT) was found to potentiate greater than or equal to 2- to 3-fold the...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1988
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC282165/ https://ncbi.nlm.nih.gov/pubmed/2845404 |
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