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IL-27 Regulates Homeostasis of the Intestinal CD4(+) Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis

IL-27 limits CD4(+) T(H)17 cell development in vitro and during inflammatory responses in the CNS. However, whether IL-27-IL-27R interactions regulate the homeostasis or function of CD4(+) T cell populations in the intestine is unknown. To test this, we examined CD4(+) T cell populations in the inte...

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Detalhes bibliográficos
Main Authors: Troy, Amy E., Zaph, Colby, Du, Yurong, Taylor, Betsy C., Guild, Katherine J., Hunter, Christopher A., Saris, Christiaan J. M., Artis, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821569/
https://ncbi.nlm.nih.gov/pubmed/19596985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802918
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