Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.

Two overlapping cDNA clones encoding human DNA topoisomerase II were identified by two independent methods. In one, a human cDNA library in phage lambda was screened by hybridization with a mixed oligonucleotide probe encoding a stretch of seven amino acids found in yeast and Drosophila DNA topoisom...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tsai-Pflugfelder, M, Liu, L F, Liu, A A, Tewey, K M, Whang-Peng, J, Knutsen, T, Huebner, K, Croce, C M, Wang, J C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7177
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