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Beneficial Effects of the Rho Kinase Inhibitor Y27632 in Murine Puromycin Aminonucleoside Nephrosis

BACKGROUND AND AIMS: Rho kinase (ROCK) inhibition reduces systemic blood pressure (BP) and decreases renal damage in animal models of kidney disease. The aim of this study was to determine if ROCK inhibition might have beneficial effects in glomerular disease processes that are independent of system...

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Autores principales: Wang, Liming, Ellis, Mathew J., Fields, Timothy A., Howell, David N., Spurney, Robert F.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821439/
https://ncbi.nlm.nih.gov/pubmed/18367845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000121531
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