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Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-α

BACKGROUND: Defective epithelial repair, excess fibroblasts and myofibroblasts, collagen overproduction and fibrosis occur in a number of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis. Pathological conversion of epithelial cells into fibrobl...

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Autors principals: Câmara, Joana, Jarai, Gabor
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821296/
https://ncbi.nlm.nih.gov/pubmed/20051102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-3-2
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