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Early Neural and Vascular Dysfunctions in Diabetic Rats Are Largely Sequelae of Increased Sorbitol Oxidation

These experiments were undertaken to assess the importance of cytoplasmic (c) sorbitol oxidation versus mitochondrial (m) pyruvate oxidation in mediating neural and vascular dysfunction attributable to hyperglycemia in diabetic rats. Increased oxidation of sorbitol is coupled to enzymatic reduction...

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Bibliografske podrobnosti
Main Authors: Ido, Yasuo, Nyengaard, Jens R., Chang, Kathy, Tilton, Ronald G., Kilo, Charles, Mylari, Banavara L., Oates, Peter J., Williamson, Joseph R.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821145/
https://ncbi.nlm.nih.gov/pubmed/19624259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2502
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