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Sclerostin Binds and Regulates the Activity of Cysteine Rich Protein 61

Sclerostin, a secreted glycoprotein, regulates osteoblast function. Using yeast two-hybrid and direct protein interaction analyses, we demonstrate that sclerostin binds the Wnt-modulating and Wnt-modulated, extracellular matrix protein, cysteine-rich protein 61 (Cyr61, CCN1), which regulates mesench...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Craig, Theodore A., Bhattacharya, Resham, Mukhopadhyay, Debabrata, Kumar, Rajiv
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821021/
https://ncbi.nlm.nih.gov/pubmed/20043874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.143
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