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Host-Guest Complexation Studied by Fluorescence Correlation Spectroscopy: Adamantane–Cyclodextrin Inclusion

The host-guest complexation between an Alexa 488 labelled adamantane derivative and β-cyclodextrin is studied by Fluorescence Correlation Spectroscopy (FCS). A 1:1 complex stoichiometry and a high association equilibrium constant of K = 5.2 × 10(4) M(−1) are obtained in aqueous solution at 25 °C and...

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Bibliographic Details
Main Authors: Granadero, Daniel, Bordello, Jorge, Pérez-Alvite, Maria Jesus, Novo, Mercedes, Al-Soufi, Wajih
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820997/
https://ncbi.nlm.nih.gov/pubmed/20162009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11010173
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