Stability of Murine Cytomegalovirus Genome after In Vitro and In Vivo Passage

While large DNA viruses are thought to have low mutation rates, only a small fraction of their genomes have been analyzed at the single-nucleotide level. Here, we defined the genetic stability of murine cytomegalovirus (MCMV) by whole-genome sequencing. Independently assembled sequences of three sis...

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Autori principali: Cheng, Tammy P., Valentine, Mark C., Gao, Jian, Pingel, Jeanette T., Yokoyama, Wayne M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820925/
https://ncbi.nlm.nih.gov/pubmed/20015993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02142-09
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