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Sterile Alpha Motif Domain-Mediated Self-Association Plays an Essential Role in Modulating the Activity of the Drosophila ETS Family Transcriptional Repressor Yan

The ETS family transcriptional repressor Yan is an important downstream target and effector of the receptor tyrosine kinase (RTK) signaling pathway in Drosophila melanogaster. Structural and biochemical studies have shown that the N-terminal sterile alpha motif (SAM) of Yan is able to self associate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Jie, Graham, Thomas G. W., Vivekanand, Pavithra, Cote, Lauren, Cetera, Maureen, Rebay, Ilaria
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820895/
https://ncbi.nlm.nih.gov/pubmed/20048052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01225-09
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