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H19 Imprinting Control Region Methylation Requires an Imprinted Environment Only in the Male Germ Line
The 2.4-kb H19 imprinting control region (H19ICR) is required to establish parent-of-origin-specific epigenetic marks and expression patterns at the Igf2/H19 locus. H19ICR activity is regulated by DNA methylation. The ICR is methylated in sperm but not in oocytes, and this paternal chromosome-specif...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820884/ https://ncbi.nlm.nih.gov/pubmed/20038532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00575-09 |
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