IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

The effect of human recombinant interleukin 4 (IL-4) on antibody production by normal peripheral blood mononuclear cells enriched for B cells was investigated. IL-4 preferentially induced IgE synthesis in vitro. In addition, a low induction of IgG production was observed, whereas IL-4 had no effect...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pène, J, Rousset, F, Brière, F, Chrétien, I, Bonnefoy, J Y, Spits, H, Yokota, T, Arai, N, Arai, K, Banchereau, J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2970644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.18.6880
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